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1. 21 CFR 101.36 — Nutrition labeling of dietary supplementsU.S. Electronic Code of Federal RegulationsThe rule that the label of a dietary supplement that is offered for sale shall bear nutrition labeling in accordance with this regulation, and the proprietary-blend rules on total weight and descending order of predominance by weight.
2. Coenzyme Q10NIH National Center for Complementary and Integrative HealthThat the heart-disease and heart-failure evidence is inconclusive, that the evidence does not support CoQ10 for statin-related muscle pain, that no serious side effects of CoQ10 have been reported, and the warfarin and insulin interactions.
3. GRAS Notice 709 — Pyrroloquinoline quinone disodium saltU.S. Food and Drug AdministrationThe food-ingredient levels proposed for PQQ disodium salt — 8 to 20 mg per 240 mL serving — and the estimated intakes. These are food levels, not a studied dose for any health effect.
4. FDA warns about heavy metal poisoning associated with certain unapproved ayurvedic drug productsU.S. Food and Drug Administration, 3 December 2025FDA's warning that some unapproved ayurvedic products contain heavy metals that are not on the label, the symptoms it lists, and its advice to talk to a health care provider first. It names other products, not this one.
5. Health Products Compliance GuidanceU.S. Federal Trade CommissionThe competent and reliable scientific evidence standard, and the rule that consumer testimonials are never sufficient to substantiate claims about the effects of a health product.
6. Complying with the Made in USA StandardU.S. Federal Trade CommissionThe all or virtually all standard that a Made in USA claim has to meet.